Nebivolol decreases systemic oxidative stress in healthy volunteers
نویسندگان
چکیده
منابع مشابه
Phenotypic differences in nebivolol metabolism and bioavailability in healthy volunteers
INTRODUCTION Nebivolol, a third-generation β-blocker, is subject to extensive first-pass metabolism and produces active β-blocking hydroxylated metabolites, like 4-OH-nebivolol. It is primarily a substrate of CYP2D6, a metabolic pathway that is under polymorphic genetic regulation. The objective of this study was to assess the metabolizer phenotype and to evaluate the interphenotype bioavailabi...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 2000
ISSN: 0306-5251
DOI: 10.1046/j.1365-2125.2000.00258.x